Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 9/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843371 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TLR7KDM4EHPGD | |
| SCHEMBL7845277 | 0.84 | GRIN1 (0.45) | GRIN1GRIN2BNOX4GABRA1GABRA5 | |
| SCHEMBL7848697 | 0.84 | TLR7 (0.32) | ALDH1A1TLR7KDM5BKDM4E | |
| SCHEMBL6088087 | 0.84 | GRIN1 (0.45) | GRIN1GRIN2BNOX4GABRA1GABRA5 | |
| SCHEMBL7847101 | 0.80 | GRIN1 (0.45) | GRIN1GRIN2BNOX4GABRA1GABRA5 | |
| SCHEMBL7837569 | 0.78 | KMT2A (0.37) | GABRA1GABRA5ALDH1A1 | |
| SCHEMBL7837651 | 0.77 | MTNR1A (0.50) | GRIN1GRIN2BALDH1A1KDM4EHPGD | |
| SCHEMBL7848879 | 0.77 | TYMS (0.35) | — | |
| SCHEMBL7849648 | 0.77 | GRIN1 (0.36) | GRIN1GRIN2BALDH1A1 | |
| SCHEMBL7848132 | 0.76 | GRIN1 (0.40) | GRIN1GRIN2BKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |