Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086540 | 0.67 | NPC1 (0.43) | LMNAALDH1A1POLBNPSR1 | |
| SCHEMBL6087716 | 0.67 | ALDH1A1 (0.39) | ALDH1A1POLB | |
| SCHEMBL31177274 | 0.67 | LMNA (0.33) | USP2LMNAHRH2COMT | |
| SCHEMBL3252312 | 0.64 | RAB9A (0.44) | LMNAALDH1A1 | |
| SCHEMBL1753026 | 0.64 | NPC1 (0.63) | ALDH1A1POLBNPSR1 | |
| SCHEMBL6088244 | 0.64 | NPC1 (0.37) | ALDH1A1POLBNPSR1 | |
| SCHEMBL6087726 | 0.64 | NPC1 (0.33) | LMNAALDH1A1POLBNPSR1 | |
| SCHEMBL6087209 | 0.63 | HIPK2 (0.34) | ALDH1A1 | |
| SCHEMBL6086442 | 0.63 | KDM4E (0.45) | LMNAALDH1A1 | |
| SCHEMBL3252316 | 0.63 | RAB9A (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056354-B2 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratinous fibers | L'OREAL (FR) | 2006-06-06 | — | — | US | claimed |
| US-20040255397-A1 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratimous fibers | L'OREAL (FR) | 2004-12-23 | — | — | US | claimed |
| EP-1412348-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLE SUBSTITUTED BY A HETEROAROMATIC RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-04-28 | — | — | EP | claimed |
| WO-2003008405-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLE SUBSTITUTED BY A HETEROAROMATIC RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2003-01-30 | — | — | WO | claimed |
| US-7056354-B2 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratinous fibers | L'OREAL (FR) | 2006-06-06 | — | — | US | disclosed |
| US-20040255397-A1 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratimous fibers | L'OREAL (FR) | 2004-12-23 | — | — | US | disclosed |
| EP-1412348-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLE SUBSTITUTED BY A HETEROAROMATIC RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003008405-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLE SUBSTITUTED BY A HETEROAROMATIC RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255397-A1 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratimous fibers | KRT18, AOC1, XRCC5 | ATR 1178/4885USP2 4474/4885LMNA 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.