Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088268 | 1.00 | PDE3B (0.32) | PDE3BPDE3AGFERMAOAMAOB | |
| SCHEMBL6090013 | 0.89 | GPR84 (0.34) | DAO | |
| SCHEMBL6089356 | 0.89 | GPR84 (0.33) | DAO | |
| SCHEMBL6089582 | 0.83 | GFER (0.33) | GFERMAOAMAOB | |
| SCHEMBL6089586 | 0.83 | GFER (0.33) | GFERMAOAMAOB | |
| SCHEMBL6091646 | 0.75 | SIRT1 (0.42) | GFERMAOAMAOB | |
| SCHEMBL6090355 | 0.75 | SIRT1 (0.42) | GFERMAOAMAOB | |
| SCHEMBL6088598 | 0.74 | GFER (0.32) | GFERDAO | |
| SCHEMBL6091001 | 0.74 | GFER (0.32) | GFER | |
| SCHEMBL6090037 | 0.74 | PDPK1 (0.39) | GFERDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |