Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088597 | 0.90 | CYSLTR1 (0.43) | PTGER4MAP4K4ALOX5APFFAR1ALOX5 | |
| SCHEMBL6087956 | 0.85 | PTGER4 (0.55) | PTGER4SLC26A4NR4A2MRGPRX4FFAR1 | |
| SCHEMBL6091423 | 0.84 | SLC26A4 (0.43) | PTGER4SLC26A4NR4A2NPC1RAB9A | |
| SCHEMBL6089761 | 0.84 | GPR132 (0.49) | PTGER4SLC26A4NR4A2NPC1RAB9A | |
| SCHEMBL6088808 | 0.82 | SLC26A4 (0.46) | PTGER4SLC26A4NR4A2NPC1RAB9A | |
| SCHEMBL6088674 | 0.82 | SLC26A4 (0.63) | PTGER4SLC26A4NR4A2NPC1RAB9A | |
| SCHEMBL6088614 | 0.81 | CYSLTR1 (0.50) | SLC26A4NR4A2NPC1RAB9AGPBAR1 | |
| SCHEMBL5725146 | 0.80 | CYSLTR1 (0.67) | GPBAR1CYSLTR1 | |
| SCHEMBL4450804 | 0.80 | PPARA (0.55) | PTGER4SLC26A4FFAR1 | |
| SCHEMBL5724957 | 0.80 | PPARA (0.55) | PTGER4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| CN-1183113-C | Tri-aryl acid derivatives as PPAR receptor ligands | ���ĵ�˹ҩ��¹�����˾ | 2005-01-05 | — | — | CN | disclosed |
| CN-1356983-A | Tri-aryl acid derivatives as PPAR receptor ligands | AVENTIS PHARM PROD INC (DE) | 2002-07-03 | — | — | CN | disclosed |