Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424866 | 0.84 | L3MBTL1 (0.50) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL623350 | 0.82 | L3MBTL1 (0.49) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL19748745 | 0.81 | L3MBTL1 (0.47) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL13806631 | 0.81 | L3MBTL1 (0.47) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL18280304 | 0.81 | L3MBTL1 (0.47) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL2336127 | 0.81 | DUSP3 (0.59) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL5693066 | 0.81 | L3MBTL1 (0.47) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL5479665 | 0.79 | L3MBTL1 (0.50) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL5164770 | 0.79 | BID (0.53) | L3MBTL1TDP1KDM4EHSD17B10BID | |
| SCHEMBL355272 | 0.79 | TDP1 (0.61) | L3MBTL1TDP1MYCKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |