Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423306 | 0.87 | GABRA1 (0.54) | GABRA1GABRB2BIDMCL1BCL2L1 | |
| SCHEMBL5164770 | 0.86 | BID (0.53) | L3MBTL1TDP1BIDMCL1BCL2L1 | |
| SCHEMBL623350 | 0.86 | L3MBTL1 (0.49) | L3MBTL1TDP1PTGS2BIDMCL1 | |
| SCHEMBL13806631 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1PTGS2BIDMCL1 | |
| SCHEMBL5693066 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1PTGS2BIDMCL1 | |
| SCHEMBL6089197 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1PTGS2BIDMCL1 | |
| SCHEMBL18280304 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1PTGS2BIDMCL1 | |
| SCHEMBL2336127 | 0.84 | DUSP3 (0.59) | L3MBTL1TDP1PTGS2KDM4EALDH1A1 | |
| SCHEMBL19748745 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1PTGS2BIDMCL1 | |
| SCHEMBL501450 | 0.83 | GABRA1 (0.46) | L3MBTL1TDP1GABRA1GABRB2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3594203-B1 | SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-08-04 | — | — | EP | disclosed |
| US-11059780-B2 | Substituted pyrrolidine compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-07-13 | — | — | US | disclosed |
| US-20200385345-A1 | SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-12-10 | — | — | US | disclosed |
| EP-3708567-A1 | METHOD FOR PREPARING BENZOFURAN DERIVATIVE | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2020-09-16 | — | — | EP | disclosed |
| EP-2470498-B1 | CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2015-02-11 | — | — | EP | disclosed |
| US-8906279-B2 | Manufacturing method of polarizing plate protective film, polarizing plate protective film, polarizing plate, and liquid crystal display device | KONICA MINOLTA OPTO, INC. (JP) | 2014-12-09 | — | — | US | disclosed |
| US-8569405-B2 | Additive mixtures for styrenic polymers | BASF SE (DE) | 2013-10-29 | — | — | US | disclosed |
| US-8518302-B2 | Stabilization of organic materials | BASF SE (DE) | 2013-08-27 | — | — | US | disclosed |
| US-8404673-B2 | Carbocyclic GlyT1 receptor antagonists | HOFFMANN-LA ROCHE INC. (US) | 2013-03-26 | — | — | US | disclosed |
| WO-2012139891-A1 | SUBSTITUTED VINYL AND ALKINYL CYCLOHEXENOLS AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2012-10-18 | — | — | WO | disclosed |
| US-5367008-A | 3-(alkoxyphenyl)benzofuran-2-ones as stabilisers | CIBA-GEIGY CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| US-5356966-A | Stabilizing organic material against oxidative, thermal or light iinduced degradation | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0608198-A1 | Cyclic diphenylacetonenitriles as stabilisers | CIBA-GEIGY AG (CH) | 1994-07-27 | — | — | EP | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |
| EP-0589839-A1 | 3-(Dihydrobenzofuran-5-yl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-03-30 | — | — | EP | disclosed |
| US-5218052-A | Increased stiffness and broadend molecular weight distribution | AMOCO CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0498603-A2 | Olefin polymerization and copolymerization process | AMOCO CORPORATION (US) | 1992-08-12 | — | — | EP | disclosed |
| EP-0181710-B1 | STAIN-RESISTANT PLASTICIZERS AND POLYVINYL CHLORIDE COMPOSITIONS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4656214-A | DIESTERS | EXXON RESEARCH & ENGINEERING CO. (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0181710-A2 | Stain-resistant plasticizers and polyvinyl chloride compositions | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059780-B2 | Substituted pyrrolidine compound and use thereof | HCRTR2, HCRTR1, CRHR2 | L3MBTL1 4380/4885TDP1 3703/4885GABRA1 245/4885 |
| US-20200385345-A1 | SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF | HCRTR2, HCRTR1, CRHR2 | L3MBTL1 4380/4885TDP1 3703/4885GABRA1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.