Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 15/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089344 | 0.85 | CYSLTR1 (0.34) | CYSLTR1CYSLTR2CYP1A2ELANEGPBAR1 | |
| SCHEMBL7463610 | 0.83 | CYSLTR1 (0.36) | CYSLTR1CYSLTR2ELANEGPBAR1 | |
| SCHEMBL6089336 | 0.77 | ALDH1A1 (0.35) | CYSLTR1CYSLTR2CYP1A2ELANE | |
| SCHEMBL6089645 | 0.74 | CYSLTR1 (0.39) | CYSLTR1CYSLTR2CYP1A2GPBAR1 | |
| SCHEMBL6089338 | 0.72 | CYP1A2 (0.37) | CYSLTR1CYSLTR2CYP1A2GPBAR1 | |
| SCHEMBL6088757 | 0.71 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6089021 | 0.70 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6089420 | 0.70 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6088877 | 0.69 | CYP1A2 (0.36) | CYSLTR1CYSLTR2CYP1A2GPBAR1 | |
| SCHEMBL6090963 | 0.68 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |