Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089635 | 0.88 | CYSLTR1 (0.34) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL6089331 | 0.77 | CYSLTR1 (0.36) | ELANECYP1A2CYSLTR1CYSLTR2 | |
| SCHEMBL6089344 | 0.72 | CYSLTR1 (0.34) | ALDH1A1KDM4EGLAGAACASP1 | |
| SCHEMBL6090963 | 0.70 | CYSLTR1 (0.46) | SMN1; SMN2MAPTCYSLTR1CYSLTR2 | |
| SCHEMBL7463610 | 0.70 | CYSLTR1 (0.36) | ELANECYSLTR1CYSLTR2 | |
| SCHEMBL6089021 | 0.69 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2 | |
| SCHEMBL6089338 | 0.68 | CYP1A2 (0.37) | ALDH1A1KDM4EGLAGAACASP1 | |
| SCHEMBL6089420 | 0.68 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2 | |
| SCHEMBL6088757 | 0.68 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2 | |
| SCHEMBL4841311 | 0.66 | ALDH1A1 (0.50) | ALDH1A1KDM4EGLAGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |