Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086306 | 0.86 | KMT2A (0.39) | RAB9APIK3CDPIK3CBKMT2AALDH1A1 | |
| SCHEMBL7836075 | 0.85 | RAB9A (0.38) | RAB9APIK3CDPIK3CBKMT2AALDH1A1 | |
| SCHEMBL6086262 | 0.81 | TP53 (0.39) | RAB9APIK3CDPIK3CBKMT2AMAPT | |
| SCHEMBL6087657 | 0.81 | TP53 (0.39) | RAB9APIK3CDPIK3CBKMT2AALDH1A1 | |
| SCHEMBL6086514 | 0.81 | PDE10A (0.40) | KMT2AALDH1A1MEN1TSHRMAPK1 | |
| SCHEMBL6086545 | 0.81 | HPGD (0.43) | KMT2AALDH1A1MEN1TSHRMAPK1 | |
| SCHEMBL6086995 | 0.78 | POLB (0.35) | KMT2AALDH1A1MEN1SMN1; SMN2TSHR | |
| SCHEMBL6086609 | 0.77 | GRIN1 (0.45) | KMT2AMEN1TSHRMAPK1LMNA | |
| SCHEMBL6086507 | 0.77 | DAO (0.45) | KMT2AALDH1A1MEN1SMN1; SMN2TSHR | |
| SCHEMBL6087421 | 0.77 | SMN1; SMN2 (0.37) | KMT2AALDH1A1MEN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |