Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086545 | 0.85 | HPGD (0.43) | POLBMEN1TSHRKMT2AMAPK1 | |
| SCHEMBL6086314 | 0.85 | HTT (0.33) | POLBMEN1TSHRKMT2AHTT | |
| SCHEMBL6086507 | 0.84 | DAO (0.45) | MEN1TSHRKMT2AMAPK1HTT | |
| SCHEMBL7846972 | 0.83 | CYP1A2 (0.34) | POLBMEN1TSHRKMT2AMAPK1 | |
| SCHEMBL6087421 | 0.82 | SMN1; SMN2 (0.37) | MEN1TSHRKMT2AMAPK1HTT | |
| SCHEMBL6086514 | 0.82 | PDE10A (0.40) | POLBMEN1TSHRKMT2AMAPK1 | |
| SCHEMBL6086609 | 0.80 | GRIN1 (0.45) | MEN1TSHRKMT2AMAPK1ADORA3 | |
| SCHEMBL7852074 | 0.79 | HTT (0.30) | HTTALDH1A1 | |
| SCHEMBL6088668 | 0.79 | POLB (0.35) | POLBMEN1TSHRKMT2AMAPK1 | |
| SCHEMBL6088271 | 0.79 | NPBWR1 (0.35) | POLBMEN1TSHRKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |