Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.43 |
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093678 | 0.86 | TP53 (0.41) | TP53PLA2G2AABCB1CCR2PTGES | |
| SCHEMBL6091628 | 0.83 | PLA2G2A (0.41) | PLA2G2AEDNRBEDNRAABCB1CCR2 | |
| SCHEMBL6091379 | 0.83 | YWHAH (0.45) | TP53ABCB1RXFP1PTGESYWHAH | |
| SCHEMBL6092174 | 0.82 | THRB (0.44) | TP53PLA2G2ACCR2RXFP1PTGES | |
| SCHEMBL6091652 | 0.82 | SERPINE1 (0.54) | PLA2G2APTGES | |
| SCHEMBL6090994 | 0.82 | TP53 (0.46) | TP53RXFP1PTGESKDM4EMEN1 | |
| SCHEMBL6089976 | 0.80 | PTGES (0.44) | PLA2G2AABCB1PTGESMEN1KMT2A | |
| SCHEMBL5735694 | 0.79 | RXFP1 (0.45) | TP53EDNRBEDNRACCR2RXFP1 | |
| SCHEMBL6091169 | 0.79 | ALDH1A1 (0.46) | PLA2G2ACCR2KDM4EALDH1A1 | |
| SCHEMBL6089483 | 0.78 | TP53 (0.44) | TP53ABCB1PTGESYWHAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | TP53 2032/4885PLA2G2A 982/4885EDNRB 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.