Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24135362 | 0.89 | PGK1 (0.37) | L3MBTL1TSHRHSD17B10MEN1HTT | |
| SCHEMBL23586637 | 0.82 | MAPK1 (0.38) | L3MBTL1MEN1KMT2AKDM4EAR | |
| SCHEMBL953239 | 0.81 | GABRP (0.49) | L3MBTL1TSHRHSD17B10MEN1HTT | |
| SCHEMBL7213412 | 0.78 | AR (0.42) | L3MBTL1TSHRHSD17B10MEN1HTT | |
| SCHEMBL18725473 | 0.75 | CSNK1A1 (0.38) | HTTGAAARALDH1A1CSNK1A1 | |
| SCHEMBL28959310 | 0.73 | NOS2 (0.50) | TSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL6512018 | 0.72 | TSHR (0.39) | TSHRHSD17B10MEN1HTTKMT2A | |
| SCHEMBL8450876 | 0.72 | TSHR (0.44) | TSHRHSD17B10MEN1HTTKMT2A | |
| SCHEMBL16416384 | 0.72 | TSHR (0.44) | TSHRHSD17B10MEN1HTTKMT2A | |
| SCHEMBL2609819 | 0.72 | TSHR (0.44) | TSHRHSD17B10MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074789-B2 | Kinase inhibitors | AMGEN INC. (US) | 2006-07-11 | — | — | US | disclosed |
| US-20040116388-A1 | triazine compoound inhibitors of enzymes that catalyze phosphoryl transfer and/or that bind ATP/GTP nucleotides | AMGEN INC. | 2004-06-17 | — | — | US | disclosed |