Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.34 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | RHOC | P08134 | 3/20 | 0.33 |
| ▸ | RHOA | P61586 | 3/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090166 | 0.87 | EDNRA (0.47) | ABCB1MAPT | |
| SCHEMBL6091451 | 0.79 | SLC2A1 (0.44) | ABCB1EGLN2EGLN1EGLN3SLC2A1 | |
| SCHEMBL6090836 | 0.76 | PPARG (0.47) | ABCB1EGLN2EGLN1EGLN3PTGER4 | |
| SCHEMBL6091368 | 0.73 | GRIN1 (0.43) | EGLN2EGLN1EGLN3SLC2A1PTGER4 | |
| SCHEMBL6093040 | 0.72 | SERPINE1 (0.45) | ABCB1SLC2A1 | |
| SCHEMBL6089976 | 0.72 | PTGES (0.44) | ABCB1SLC2A1PTGER4MAPT | |
| SCHEMBL5749488 | 0.72 | PTGER4 (0.46) | ABCB1SLC2A1PTGER4HDAC1HDAC8 | |
| SCHEMBL6092421 | 0.71 | PTGES (0.57) | ABCB1SLC2A1PTGER4 | |
| SCHEMBL6093252 | 0.71 | GRIN1 (0.45) | ABCB1SLC2A1PTGER4HDAC1HDAC8 | |
| SCHEMBL5748986 | 0.70 | PTGER4 (0.42) | ABCB1SLC2A1PTGER4HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | ABCB1 1475/4885EGLN2 529/4885EGLN1 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.