Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 10/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091451 | 0.93 | SLC2A1 (0.44) | PTGESPLA2G2APPARGABCB1SLC2A1 | |
| SCHEMBL6090836 | 0.93 | PPARG (0.47) | PTGESPPARGABCB1PTGER4MEN1 | |
| SCHEMBL6091652 | 0.88 | SERPINE1 (0.54) | PTGESPLA2G2APPARGPTGES2 | |
| SCHEMBL6091492 | 0.86 | THRB (0.43) | PTGESPLA2G2APPARGMEN1MAPT | |
| SCHEMBL6091368 | 0.86 | GRIN1 (0.43) | PTGESPLA2G2APPARGSLC2A1HSPH1 | |
| SCHEMBL5749488 | 0.85 | PTGER4 (0.46) | PTGESPLA2G2APPARGABCB1SLC2A1 | |
| SCHEMBL6093040 | 0.84 | SERPINE1 (0.45) | PTGESPLA2G2APPARGABCB1SLC2A1 | |
| SCHEMBL6092421 | 0.83 | PTGES (0.57) | PTGESPPARGABCB1SLC2A1PTGER4 | |
| SCHEMBL6091169 | 0.83 | ALDH1A1 (0.46) | PLA2G2APPARGSLC2A1CYP3A4MAPT | |
| SCHEMBL5748986 | 0.82 | PTGER4 (0.42) | PTGESPLA2G2APPARGABCB1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | PTGES 4/4885PLA2G2A 982/4885PPARG 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.