Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CCR9 | P51686 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089976 | 0.93 | PTGES (0.44) | PPARGABCB1PTGER4PTGES2PTGES | |
| SCHEMBL6091451 | 0.86 | SLC2A1 (0.44) | PPARGABCB1PTGER4PTGESEGLN2 | |
| SCHEMBL6091652 | 0.80 | SERPINE1 (0.54) | PPARGPTGES2PTGESSERPINE1CCR9 | |
| SCHEMBL6091368 | 0.78 | GRIN1 (0.43) | PPARGPTGER4PTGESEGLN2EGLN1 | |
| SCHEMBL6091492 | 0.78 | THRB (0.43) | PPARGPTGES2PTGESSERPINE1MAPT | |
| SCHEMBL6090166 | 0.78 | EDNRA (0.47) | PPARGABCB1MAPTMEN1TSHR | |
| SCHEMBL6093040 | 0.77 | SERPINE1 (0.45) | PPARGABCB1PTGES2PTGESSERPINE1 | |
| SCHEMBL4701667 | 0.76 | PTGES (0.46) | PPARGPTGESMAPTMEN1KMT2A | |
| SCHEMBL6090163 | 0.76 | ABCB1 (0.41) | ABCB1PTGER4EGLN2EGLN1EGLN3 | |
| SCHEMBL5749488 | 0.76 | PTGER4 (0.46) | PPARGABCB1PTGER4PTGESSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | PPARG 481/4885ABCB1 1475/4885PTGER4 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.