Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091230 | 1.00 | KYNU (0.59) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL2396183 | 0.95 | KYNU (0.57) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL2398018 | 0.95 | KYNU (0.57) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL3617397 | 0.94 | KYNU (0.56) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL3824400 | 0.94 | KYNU (0.56) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL25240531 | 0.93 | CTSK (0.52) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL25288547 | 0.93 | CTSK (0.52) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL18686857 | 0.91 | CTSK (0.50) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL24112557 | 0.91 | CTSK (0.50) | KYNUALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL2399710 | 0.88 | CTSK (0.50) | KYNUALDH1A1ALOX15CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287402-A1 | Cathepsin inhibitors | MERCK FROSST CANADA & CO. (CA) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287402-A1 | Cathepsin inhibitors | CTSB, CTSK, CTSS | KYNU 1454/4885ALDH1A1 2983/4885ALOX15 2746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.