SCHEMBL6091360

SCHEMBL6091360

Cc1ccccc1NC(=O)N(CCC(c1ccc(Cl)cc1)N(C)C)OC(=O)C(=O)ON(CCC(c1ccc(Cl)cc1)N(C)C)C(=O)Nc1ccccc1C

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 11/20 0.53
OPRM1 P35372 2/20 0.42
MEN1 O00255 1/20 0.42
OPRD1 P41143 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5454269 0.83 UTS2R (0.61) UTS2R
SCHEMBL6093296 0.82 UTS2R (0.54) UTS2RL3MBTL1
SCHEMBL6094112 0.82 UTS2R (0.56) UTS2RL3MBTL1
SCHEMBL6092652 0.81 UTS2R (0.56) UTS2ROPRM1MEN1KMT2A
SCHEMBL6091146 0.80 UTS2R (0.53) UTS2ROPRM1MEN1KMT2ACYP2D6
SCHEMBL6093163 0.79 UTS2R (0.53) UTS2RMEN1KMT2AL3MBTL1
SCHEMBL6090694 0.78 UTS2R (0.60) UTS2ROPRM1MEN1OPRD1KMT2A
SCHEMBL6092916 0.78 UTS2R (0.55) UTS2R
SCHEMBL5459489 0.70 UTS2R (1.00) UTS2R
SCHEMBL5458491 0.66 UTS2R (0.62) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006135694-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2006-12-21 WO claimed