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SCHEMBL6094112

SCHEMBL6094112

CN(C)C(CCN(OC(=O)C(=O)ON(CCC(c1ccc(Cl)cc1)N(C)C)C(=O)Nc1ccc(Oc2ccccc2)cc1)C(=O)Nc1ccc(Oc2ccccc2)cc1)c1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ UTS2R Q9UKP6 4/20 0.56
▸ NPY5R Q15761 12/20 0.53
▸ FNTA P49354 2/20 0.45
▸ FNTB P49356 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ NPY2R P49146 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6093296 0.91 UTS2R (0.54) UTS2RNPY5RALDH1A1L3MBTL1
SCHEMBL6093163 0.90 UTS2R (0.53) UTS2RFNTAFNTBALDH1A1L3MBTL1
SCHEMBL6092652 0.87 UTS2R (0.56) UTS2R
SCHEMBL6092916 0.84 UTS2R (0.55) UTS2R
SCHEMBL5463949 0.84 UTS2R (0.64) UTS2RNPY5RFNTAFNTBALDH1A1
SCHEMBL6091360 0.82 UTS2R (0.53) UTS2RL3MBTL1
SCHEMBL6091146 0.81 UTS2R (0.53) UTS2RALDH1A1
SCHEMBL6091406 0.81 UTS2R (0.62) UTS2RNPY5RFNTAFNTBALDH1A1
SCHEMBL5458491 0.75 UTS2R (0.62) UTS2R
SCHEMBL5463931 0.73 UTS2R (0.61) UTS2RFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006135694-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2006-12-21 — — WO claimed
WO-2006135694-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2006-12-21 — — WO disclosed