Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452756 | 0.83 | UTS2R (0.61) | UTS2RCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6093296 | 0.81 | UTS2R (0.54) | UTS2RKDM4EALDH1A1 | |
| SCHEMBL6094112 | 0.81 | UTS2R (0.56) | UTS2RALDH1A1 | |
| SCHEMBL6091360 | 0.80 | UTS2R (0.53) | UTS2RCYP2D6CYP2C19OPRM1MEN1 | |
| SCHEMBL6091970 | 0.78 | UTS2R (0.59) | UTS2RCYP2D6CYP2C9CYP2C19OPRM1 | |
| SCHEMBL6092652 | 0.78 | UTS2R (0.56) | UTS2ROPRM1MEN1RAB9AKMT2A | |
| SCHEMBL6093163 | 0.76 | UTS2R (0.53) | UTS2RALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL6092916 | 0.74 | UTS2R (0.55) | UTS2RRAB9A | |
| SCHEMBL5455926 | 0.69 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6092345 | 0.69 | CNR1 (0.52) | UTS2ROPRM1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | claimed |
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | disclosed |