Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.61 |
| ▸ | BACE1 | P56817 | 4/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503711 | 0.87 | ALDH1A1 (0.65) | GSK3BBACE1EPHX2FAAHCNR2 | |
| SCHEMBL12040547 | 0.82 | GABBR2 (0.53) | CNR2MAOBKDM4EMEN1MAPT | |
| SCHEMBL6091145 | 0.82 | GABBR2 (0.53) | CNR2MAOBKDM4EMEN1MAPT | |
| SCHEMBL7054733 | 0.81 | GSK3B (0.76) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL7054731 | 0.81 | GSK3B (0.76) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL6090681 | 0.79 | RARB (0.51) | MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6093637 | 0.78 | F3 (0.55) | GSK3BBACE1MEN1MAPTKMT2A | |
| SCHEMBL527827 | 0.78 | GSK3B (0.80) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL7999149 | 0.78 | GSK3B (0.83) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL8740053 | 0.78 | GSK3B (0.80) | GSK3BBACE1ABCG2MAOBSLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-04-06 | — | — | US | claimed |
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | PMP22, ADCYAP1R1, CYP11B2 | GSK3B 419/4885BACE1 461/4885EPHX2 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.