Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.42 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089609 | 0.93 | PTGES (0.42) | THRBPTGESTP53PLA2G2AKCNQ3 | |
| SCHEMBL6092174 | 0.88 | THRB (0.44) | THRBPTGESTP53PLA2G2ASERPINE1 | |
| SCHEMBL6089976 | 0.86 | PTGES (0.44) | PTGESPLA2G2AGRIN1GRIN2BPPARG | |
| SCHEMBL6089685 | 0.82 | GRIN1 (0.44) | THRBPTGESTP53PLA2G2AGRIN1 | |
| SCHEMBL6091691 | 0.79 | TP53 (0.44) | THRBPTGESTP53PLA2G2AGSK3B | |
| SCHEMBL6091652 | 0.79 | SERPINE1 (0.54) | PTGESPLA2G2ASERPINE1PPARGPTGES2 | |
| SCHEMBL6091451 | 0.79 | SLC2A1 (0.44) | PTGESPLA2G2AGRIN1GRIN2BPPARG | |
| SCHEMBL6090836 | 0.78 | PPARG (0.47) | PTGESSERPINE1PPARGMAPTMEN1 | |
| SCHEMBL6091172 | 0.77 | TP53 (0.41) | THRBPTGESTP53PPARGGSK3B | |
| SCHEMBL5747009 | 0.77 | THRB (0.45) | THRBTP53SERPINE1PPARGGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | THRB 1146/4885PTGES 4/4885TP53 2032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.