Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089855 | 0.92 | HRH3 (0.42) | PDGFRBFGFR1KDRL3MBTL1HRH3 | |
| SCHEMBL4410704 | 0.87 | PDGFRB (0.43) | PDGFRBFGFR1KDRSIGMAR1KMT2A | |
| SCHEMBL6092642 | 0.83 | ALOX15 (0.42) | L3MBTL1KMT2AALOX15MAPT | |
| SCHEMBL6091353 | 0.81 | ALOX15 (0.45) | L3MBTL1KMT2AALOX15MAPT | |
| SCHEMBL5401668 | 0.76 | L3MBTL1 (0.45) | PDGFRBFGFR1KDRL3MBTL1KMT2A | |
| SCHEMBL6220089 | 0.75 | SPR (0.41) | MAPT | |
| SCHEMBL6088742 | 0.74 | KDM4E (0.46) | PDGFRBFGFR1KDRKMT2ACHEK1 | |
| SCHEMBL5414923 | 0.72 | SRC (0.44) | PDGFRBFGFR1KDRLTA4HMAPT | |
| SCHEMBL6090420 | 0.72 | CHEK1 (0.43) | PDGFRBFGFR1KDRKMT2ACHEK1 | |
| SCHEMBL6090987 | 0.72 | CHEK1 (0.51) | PDGFRBFGFR1KDRKMT2ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |