Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 16/20 | 0.47 |
| ▸ | EDNRB | P24530 | 14/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092838 | 0.79 | EDNRB (0.45) | EDNRAEDNRB | |
| SCHEMBL6089927 | 0.70 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL8900846 | 0.64 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL5151691 | 0.63 | MAOB (0.51) | EDNRAEDNRB | |
| SCHEMBL4923088 | 0.63 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL5156072 | 0.63 | FABP4 (0.51) | EDNRAEDNRB | |
| SCHEMBL3427834 | 0.63 | TSHR (0.55) | — | |
| SCHEMBL3566668 | 0.62 | PLA2G2A (0.68) | PLA2G2A | |
| SCHEMBL5899759 | 0.62 | MAPT (0.68) | — | |
| SCHEMBL12389168 | 0.61 | RAB9A (0.55) | EDNRAEDNRBPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | EDNRA 155/4885EDNRB 226/4885PLA2G2A 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.