Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093300 | 0.89 | ALDH1A1 (0.69) | KMT2AATMUTS2RPOLBALDH1A1 | |
| SCHEMBL6093716 | 0.84 | UTS2R (0.62) | KMT2AATMUTS2RMEN1CNR2 | |
| SCHEMBL4729679 | 0.79 | UTS2R (0.61) | UTS2ROPRM1OPRD1ALDH1A1 | |
| SCHEMBL6092298 | 0.76 | UTS2R (1.00) | UTS2R | |
| Hydrochloric Acid SCHEMBL5464571 | 0.75 | UTS2R (0.98) | UTS2R | |
| SCHEMBL4730705 | 0.74 | UTS2R (0.65) | UTS2RALDH1A1 | |
| SCHEMBL6091221 | 0.74 | UTS2R (0.61) | KMT2AUTS2ROPRM1MEN1 | |
| SCHEMBL2009552 | 0.73 | SLC6A9 (0.79) | KMT2AATMUTS2RPOLBALDH1A1 | |
| SCHEMBL275229 | 0.73 | POLB (0.80) | KMT2AATMPOLBALDH1A1MEN1 | |
| SCHEMBL16560992 | 0.72 | KMT2A (0.74) | KMT2AATMALDH1A1MEN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | disclosed |