Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CNR2 | P34972 | 3/20 | 0.61 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092302 | 0.89 | KMT2A (0.64) | ALDH1A1CNR2UTS2RCNR1KMT2A | |
| SCHEMBL4729679 | 0.81 | UTS2R (0.61) | ALDH1A1UTS2RL3MBTL1NPC1 | |
| SCHEMBL4730705 | 0.76 | UTS2R (0.65) | ALDH1A1UTS2R | |
| SCHEMBL6093294 | 0.76 | UTS2R (1.00) | CNR2UTS2R | |
| Hydrochloric Acid SCHEMBL5457616 | 0.75 | UTS2R (0.98) | CNR2UTS2R | |
| SCHEMBL6092762 | 0.73 | UTS2R (0.60) | ALDH1A1UTS2RCNR1KMT2AMEN1 | |
| SCHEMBL6093716 | 0.73 | UTS2R (0.62) | CNR2UTS2RCNR1KMT2AMEN1 | |
| SCHEMBL3660216 | 0.72 | DRD2 (0.46) | ALDH1A1UTS2RCNR1KMT2AMEN1 | |
| SCHEMBL1882632 | 0.72 | ALDH1A1 (0.46) | ALDH1A1CNR2CNR1ATMHDAC1 | |
| SCHEMBL4731502 | 0.71 | UTS2R (0.55) | UTS2RKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | disclosed |