Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25059409 | 0.91 | FDPS (0.51) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL19879709 | 0.88 | FDPS (0.53) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL6091366 | 0.78 | FDPS (0.55) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL5673422 | 0.75 | FDPS (0.41) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL6092755 | 0.74 | FDPS (0.41) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL828256 | 0.72 | FDPS (0.53) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL22511537 | 0.72 | FDPS (0.60) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL25031428 | 0.72 | FDPS (0.46) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL29851369 | 0.71 | FDPS (0.59) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL828257 | 0.71 | FDPS (0.59) | FDPSALDH1A1SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270714-A1 | Novel n-substituted 2-aminopyridine derivatives | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270714-A1 | Novel n-substituted 2-aminopyridine derivatives | NOS1, NOS2, NOS3 | FDPS 878/4885ALDH1A1 552/4885SMN1; SMN2 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.