SCHEMBL6853283

SCHEMBL6853283

C/C(=C\N1CCCC1)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5145532 1.00 TDP1 (0.32) TDP1LMNAALOX15BLMPMP22
SCHEMBL489074 0.98 L3MBTL1 (0.34) TDP1LMNAALOX15BLMPMP22
SCHEMBL842712 0.98 L3MBTL1 (0.34) TDP1LMNAALOX15BLMPMP22
SCHEMBL1696446 0.93 TDP1 (0.33) TDP1LMNAALOX15BLMPMP22
SCHEMBL150342 0.83 SMN1; SMN2 (0.42) L3MBTL1
SCHEMBL3107041 0.83 CA2 (0.33)
SCHEMBL609261 0.83 SMN1; SMN2 (0.42) L3MBTL1
SCHEMBL1257392 0.76 AKR1C3 (0.35) LMNA
SCHEMBL29238419 0.73 RECQL (0.37) LMNA
SCHEMBL8396991 0.71 L3MBTL1 (0.35) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787016-B2 ELECTROPHORESIS CHANNEL SIEVING AND COATING COMPOSITION OF BUFFERED AQUEOUS SOLUTION OF A SIEVING POLYMER AND A CHANNEL COATING POLYMER IN GIVEN WEIGHT RATIO, WHERE THE COATING POLYMER IS LESS WATER SOLUBLE THAN THE SIEVING POLYMER ACLARA BIOSCIENCES, INC. 2004-09-07 US disclosed
US-20020029968-A1 Dynamic coating with linear polymer mixture for electrophoresis ACLARA BIOSCIENCES, INC. 2002-03-14 US disclosed