SCHEMBL842712

SCHEMBL842712

C/C(=C\N1CCCCC1)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
USP2 O75604 1/20 0.32
ALOX12 P18054 1/20 0.32
F2 P00734 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL489074 1.00 L3MBTL1 (0.34) L3MBTL1NPC1ALDH1A1LMNAUSP2
SCHEMBL6853283 0.98 TDP1 (0.32) L3MBTL1LMNATDP1ALOX15BLM
SCHEMBL5145532 0.98 TDP1 (0.32) L3MBTL1LMNATDP1ALOX15BLM
SCHEMBL1696446 0.91 TDP1 (0.33) LMNATDP1ALOX15BLMPMP22
SCHEMBL3107041 0.81 CA2 (0.33)
SCHEMBL150342 0.81 SMN1; SMN2 (0.42) L3MBTL1NPC1ALDH1A1USP2ALOX12
SCHEMBL609261 0.81 SMN1; SMN2 (0.42) L3MBTL1NPC1ALDH1A1USP2ALOX12
SCHEMBL1257392 0.79 AKR1C3 (0.35) ALDH1A1LMNAUSP2ALOX12
SCHEMBL8396991 0.74 L3MBTL1 (0.35) L3MBTL1NPC1ALDH1A1F2DPP7
SCHEMBL6157888 0.72 L3MBTL1 (0.35) L3MBTL1NPC1F2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541013-B2 Amphiphilic terpolymer having pH-sensitive hydrophobic units derived from a polyunsaturated fatty acid (9,12-Octadecadienoic Acid), hydrophilic units with polar groups (acrylic acid), and temperature-sensitive units (acryloylpiperidine), useful for drug delivery AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-09-24 US claimed
US-8512757-B2 Micelles for drug delivery AGENCY FOR SCIENCE, TECHOLOGY AND RESEARCH (SG) 2013-08-20 US claimed
EP-1765894-B9 NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS AGENCY SCIENCE TECH & RES (SG) 2012-08-01 EP claimed
EP-1765894-B1 NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS AGENCY SCIENCE TECH & RES (SG) 2012-03-28 EP claimed
US-20100159019-A1 Micelles For Drug Delivery AGENCY OF SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-06-24 US claimed
EP-2035488-A1 MICELLES FOR DRUG DELIVERY Agency for Science, Technology and Research (SG) 2009-03-18 EP claimed
US-20080182959-A1 Novel Temperature and pH Sensitive Copolymers AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2008-07-31 US claimed
WO-2008004978-A1 MICELLES FOR DRUG DELIVERY AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-01-10 WO claimed
US-7316816-B2 Temperature and pH sensitive copolymers AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH (SG) 2008-01-08 US claimed
EP-1765894-A1 NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS Agency for Science, Technology and Research (SG) 2007-03-28 EP claimed
WO-2005121196-A1 NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-12-22 WO claimed
US-20050277739-A1 Amphiphilic terpolymer having pH-sensitive hydrophobic units derived from a polyunsaturated fatty acid (9,12-Octadecadienoic Acid), hydrophilic units with polar groups (acrylic acid), and temperature-sensitive units (acryloylpiperidine); lower critical solution temperature decreases as pH decreases AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2005-12-15 US claimed
US-9987221-B2 Injectable hydrogel compositions BOSTON SCIENTIFIC SCIMED, INC. (US) 2018-06-05 US disclosed
US-8541013-B2 Amphiphilic terpolymer having pH-sensitive hydrophobic units derived from a polyunsaturated fatty acid (9,12-Octadecadienoic Acid), hydrophilic units with polar groups (acrylic acid), and temperature-sensitive units (acryloylpiperidine), useful for drug delivery AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-09-24 US disclosed
US-8512757-B2 Micelles for drug delivery AGENCY FOR SCIENCE, TECHOLOGY AND RESEARCH (SG) 2013-08-20 US disclosed
EP-1765894-B9 NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS AGENCY SCIENCE TECH & RES (SG) 2012-08-01 EP disclosed
WO-2005121196-A1 NOVEL TEMPERATURE AND PH SENSITIVE COPOLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-12-22 WO disclosed
US-20050277739-A1 Amphiphilic terpolymer having pH-sensitive hydrophobic units derived from a polyunsaturated fatty acid (9,12-Octadecadienoic Acid), hydrophilic units with polar groups (acrylic acid), and temperature-sensitive units (acryloylpiperidine); lower critical solution temperature decreases as pH decreases AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2005-12-15 US disclosed
US-6787016-B2 ELECTROPHORESIS CHANNEL SIEVING AND COATING COMPOSITION OF BUFFERED AQUEOUS SOLUTION OF A SIEVING POLYMER AND A CHANNEL COATING POLYMER IN GIVEN WEIGHT RATIO, WHERE THE COATING POLYMER IS LESS WATER SOLUBLE THAN THE SIEVING POLYMER ACLARA BIOSCIENCES, INC. 2004-09-07 US disclosed
US-20020029968-A1 Dynamic coating with linear polymer mixture for electrophoresis ACLARA BIOSCIENCES, INC. 2002-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100159019-A1 Micelles For Drug Delivery ABCC1, MTDH, CHMP4B L3MBTL1 600/4885NPC1 590/4885ALDH1A1 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.