Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 20/20 | 0.60 |
| ▸ | CTSS | P25774 | 18/20 | 0.60 |
| ▸ | CTSK | P43235 | 17/20 | 0.60 |
| ▸ | CTSB | P07858 | 14/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14673225 | 0.90 | CTSL (0.74) | CTSLCTSSCTSKCTSB | |
| SCHEMBL14673490 | 0.89 | CTSL (0.72) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2155014 | 0.88 | CTSK (0.71) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2155081 | 0.84 | CTSL (0.82) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5672359 | 0.84 | CTSL (0.82) | CTSLCTSSCTSKCTSB | |
| SCHEMBL14673635 | 0.82 | CTSL (0.58) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2157327 | 0.81 | CTSL (0.85) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2156488 | 0.81 | CTSL (0.55) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2156497 | 0.79 | CTSK (0.70) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2155733 | 0.79 | CTSL (0.54) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287402-A1 | Cathepsin inhibitors | MERCK FROSST CANADA & CO. (CA) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287402-A1 | Cathepsin inhibitors | CTSB, CTSK, CTSS | CTSL 8/4885CTSS 3/4885CTSK 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.