Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.48 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | TP53 | P04637 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092352 | 0.92 | SMN1; SMN2 (0.53) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6093781 | 0.86 | MAPT (0.53) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6092024 | 0.85 | SMN1; SMN2 (0.51) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6093689 | 0.84 | MAPT (0.59) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4368880 | 0.84 | MMP2 (0.60) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4372123 | 0.83 | ALDH1A1 (0.49) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4371250 | 0.80 | METAP1 (0.58) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4371270 | 0.80 | NR2E3 (0.59) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6090851 | 0.78 | MAPT (0.50) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4372536 | 0.78 | MAPT (0.50) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | MERCK SHARP & DOHME CORP. | 2006-02-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | AR, SHBG, BRCA1 | MAPT 2814/4885RAB9A 4310/4885ALDH1A1 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.