Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093781 | 0.88 | MAPT (0.53) | SMN1; SMN2HTTALDH1A1TP53RAB9A | |
| SCHEMBL4372123 | 0.87 | ALDH1A1 (0.49) | SMN1; SMN2LMNAHTTALDH1A1TP53 | |
| SCHEMBL6092686 | 0.85 | MAPT (0.51) | SMN1; SMN2LMNAHTTALDH1A1TP53 | |
| SCHEMBL6092352 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTALDH1A1TP53RAB9A | |
| SCHEMBL4367511 | 0.81 | METAP1 (0.56) | SMN1; SMN2ALDH1A1TP53RAB9AKDM4E | |
| SCHEMBL4363565 | 0.81 | METAP1 (0.56) | SMN1; SMN2ALDH1A1TP53RAB9AKDM4E | |
| SCHEMBL13624155 | 0.81 | METAP1 (0.56) | SMN1; SMN2ALDH1A1TP53RAB9AKDM4E | |
| SCHEMBL6094823 | 0.79 | LMNA (0.53) | SMN1; SMN2LMNAALDH1A1TP53RAB9A | |
| SCHEMBL6091959 | 0.79 | LMNA (0.53) | SMN1; SMN2LMNAALDH1A1TP53RAB9A | |
| SCHEMBL4371236 | 0.79 | ROCK2 (0.47) | SMN1; SMN2LMNAALDH1A1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | MERCK SHARP & DOHME CORP. | 2006-02-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | AR, SHBG, BRCA1 | SMN1; SMN2 2413/4885LMNA 2221/4885HTT 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.