Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090390 | 0.85 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1LMNAHPGD | |
| SCHEMBL5739057 | 0.84 | KMT2A (0.46) | KMT2ASMN1; SMN2MEN1LMNAHPGD | |
| SCHEMBL6091126 | 0.82 | KMT2A (0.44) | KMT2ASMN1; SMN2MEN1LMNAHPGD | |
| SCHEMBL6089812 | 0.82 | TP53 (0.46) | KMT2ASMN1; SMN2MEN1LMNAHPGD | |
| SCHEMBL6091573 | 0.78 | NOD2 (0.56) | KMT2ASMN1; SMN2MEN1LMNAHPGD | |
| SCHEMBL19831104 | 0.77 | MAPT (0.47) | LMNAMAPTKDM4EMAPK1HTT | |
| SCHEMBL5214927 | 0.75 | CCR2 (0.59) | KMT2ASMN1; SMN2LMNAHPGDMAPT | |
| SCHEMBL671128 | 0.74 | EDNRB (0.50) | KMT2AMEN1LMNAMAPTCYP19A1 | |
| SCHEMBL22760403 | 0.74 | TSHR (0.46) | KMT2ASMN1; SMN2MEN1LMNAHPGD | |
| SCHEMBL28474638 | 0.74 | PDGFRA (0.44) | KMT2ASMN1; SMN2MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | KMT2A 3542/4885SMN1; SMN2 4402/4885MEN1 3878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.