Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760129 | 0.84 | ALDH1A1 (0.50) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL22760408 | 0.82 | PIM1 (0.42) | TSHRPIM1PIM2MAPTLMNA | |
| SCHEMBL22760162 | 0.80 | TSHR (0.47) | TSHRMAPTLMNAKDM4EGAA | |
| SCHEMBL5214927 | 0.77 | CCR2 (0.59) | TSHRMAPTLMNAGAAKMT2A | |
| SCHEMBL22760402 | 0.77 | NOD2 (0.60) | TSHRMAPTLMNAKDM4EGAA | |
| SCHEMBL1504118 | 0.76 | MAPT (0.55) | TSHRMAPTLMNAKDM4EGAA | |
| SCHEMBL4886339 | 0.75 | PLA2G2A (0.55) | TSHRMAPTLMNAKDM4EGAA | |
| SCHEMBL5739057 | 0.75 | KMT2A (0.46) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL22760543 | 0.74 | ALDH1A1 (0.54) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL6092827 | 0.74 | KMT2A (0.49) | MAPTLMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |