Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186630 | 1.00 | GPR119 (0.37) | GPR119MCHR1CYP2C9DPP4KCNH2 | |
| SCHEMBL611867 | 0.97 | GPR119 (0.35) | GPR119MCHR1CYP2C9DPP4KCNH2 | |
| SCHEMBL611612 | 0.97 | GPR119 (0.35) | GPR119MCHR1CYP2C9DPP4KCNH2 | |
| SCHEMBL611613 | 0.97 | GPR119 (0.35) | GPR119MCHR1CYP2C9DPP4KCNH2 | |
| SCHEMBL611548 | 0.93 | DPP4 (0.40) | GPR119DPP4KCNH2DPP8DPP9 | |
| SCHEMBL611812 | 0.89 | MCHR1 (0.38) | GPR119MCHR1DPP4KCNH2DPP8 | |
| SCHEMBL13186502 | 0.89 | MCHR1 (0.38) | GPR119MCHR1DPP4KCNH2DPP8 | |
| SCHEMBL10058415 | 0.88 | GPR119 (0.47) | GPR119MCHR1DPP4 | |
| SCHEMBL10058402 | 0.88 | MCHR1 (0.36) | GPR119MCHR1CYP2C9DPP4KCNH2 | |
| SCHEMBL13186503 | 0.87 | MCHR1 (0.35) | GPR119MCHR1DPP4KCNH2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-02-16 | — | — | US | claimed |
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | GPR119, GPR132, FFAR2 | GPR119 1/4885MCHR1 498/4885CYP2C9 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.