Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533987 | 0.76 | SMN1; SMN2 (0.55) | MAPTMAPK1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL6093891 | 0.75 | SMN1; SMN2 (0.57) | MAPTMAPK1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL4246402 | 0.75 | SMN1; SMN2 (0.54) | MAPTMAPK1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL29262338 | 0.75 | MAPT (0.47) | MAPTMAPK1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL10957904 | 0.74 | HSD17B10 (0.54) | MAPTMAPK1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL15294555 | 0.74 | SMN1; SMN2 (0.53) | MAPTMAPK1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8906504 | 0.74 | L3MBTL1 (0.54) | MAPTMAPK1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3737238 | 0.74 | SMN1; SMN2 (0.53) | MAPTMAPK1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL4244735 | 0.73 | MAPT (0.52) | MAPTMAPK1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1507162 | 0.73 | CACNA1H (0.51) | MAPTMAPK1SMN1; SMN2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142365-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-06-29 | — | — | US | disclosed |
| US-7030150-B2 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-04-18 | — | — | US | disclosed |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142365-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | MAPT 4679/4885MAPK1 4322/4885SMN1; SMN2 1189/4885 |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | MAPT 4679/4885MAPK1 4322/4885SMN1; SMN2 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.