SCHEMBL609434

SCHEMBL609434

CCCOc1cccc(C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 1.00
NR1H4 Q96RI1 4/20 0.74
PLA2G4B P0C869 2/20 0.68
NR4A2 P43354 1/20 0.61
SMPD1 P17405 3/20 0.60
MEP1B Q16820 1/20 0.60
PLA2G2A P14555 1/20 0.58
KAT6A Q92794 1/20 0.58
NPC1 O15118 1/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
RAB9A P51151 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
AKR1C3 P42330 1/20 0.56
PTPN11 Q06124 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3315904 0.92 KMT2A (0.84) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL2455314 0.92 KMT2A (0.84) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL15766225 0.90 KMT2A (0.82) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL8086388 0.90 KMT2A (0.82) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL8080220 0.90 KMT2A (0.82) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL8081150 0.90 KMT2A (0.82) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL7822821 0.90 KMT2A (0.82) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL7047692 0.90 KMT2A (0.82) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL2887568 0.90 KMT2A (0.82) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A
SCHEMBL8082044 0.90 KMT2A (0.82) KMT2ANR1H4PLA2G4BSMPD1PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100022799-A1 CARBONYLATION OF CONJUGATED DIENES LUCITE INTERNATIONAL UK LIMITED (GB) 2010-01-28 US claimed
CN-101563310-A Carbonylation of conjugated dienes LUCITE INT UK LTD (GB) 2009-10-21 CN claimed
EP-2094635-A1 CARBONYLATION OF CONJUGATED DIENES Lucite International UK Limited (GB) 2009-09-02 EP claimed
WO-2008075108-A1 CARBONYLATION OF CONJUGATED DIENES LUCITE INTERNATIONAL UK LIMITED (GB) 2008-06-26 WO claimed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
CN-117304205-A Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof 中国科学院广州生物医药与健康研究院 2023-12-29 CN disclosed
EP-2807162-B1 SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF Bayer Pharma AG (DE) 2017-06-07 EP disclosed
CN-104411707-B Substituted phenylimidazopyrazoles and their use 拜耳药业股份公司 2017-03-01 CN disclosed
EP-1660507-B2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME MILLENNIUM PHARM INC (US) 2017-01-04 EP disclosed
EP-2651417-B1 ASK1 INHIBITING PYRROLOPYRIMIDINE DERIVATIVES CALCHAN LTD (GB) 2016-11-30 EP disclosed
US-9394309-B2 Substituted phenylimidazopyrazoles and their use BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-07-19 US disclosed
WO-2016091789-A1 DERIVATIVES OF 2-PHENYL-7,7a-DIHYDRO-3aH-PYRANO[3,4-d]OXAZOLE-6(4H)-ONE CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2016-06-16 WO disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed
EP-0595995-A4 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LAB (US) 1994-08-24 EP disclosed
EP-0603786-A2 Alkyl-substituted hydroquinone derivatives for use in ferro-electric liquid crystal mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-29 EP disclosed
EP-0595995-A1 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY. ABBOTT LAB (US) 1994-05-11 EP disclosed
WO-1993002037-A1 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LABORATORIES (US) 1993-02-04 WO disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed
US-3971863-A Coated heat fusible injection moldable phenol-aldehyde pellets GENERAL ELECTRIC COMPANY (US) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS KMT2A 4371/4885NR1H4 2049/4885PLA2G4B 1080/4885
US-20100022799-A1 CARBONYLATION OF CONJUGATED DIENES CBR3, CBR1, CA5B KMT2A 1801/4885NR1H4 1241/4885PLA2G4B 1180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.