Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 4/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 3/20 | 0.31 |
| ▸ | PRKCH | P24723 | 3/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096903 | 0.86 | GPR84 (0.42) | GPR84PTPRCPTPRFPTPN1CDC25B | |
| SCHEMBL6096170 | 0.84 | CYP2A6 (0.41) | GPR84PTPRCPTPRFPTPN1CDC25B | |
| SCHEMBL6097076 | 0.84 | GPR84 (0.40) | HTR2AGPR84PTPRCPTPRFPTPN1 | |
| SCHEMBL6094641 | 0.84 | HTR2A (0.44) | HTR2AAURKAAURKBNR4A2ABL1 | |
| SCHEMBL6097207 | 0.79 | AR (0.44) | HTR2APRKCBNR4A2PRKCAPRKCH | |
| SCHEMBL6097734 | 0.78 | PRKCB (0.54) | PTPRCPTPRFPTPN1CDC25BPRKCB | |
| SCHEMBL6097121 | 0.74 | HTR2A (0.40) | HTR2AGPR84PTPRCPTPRFPTPN1 | |
| SCHEMBL6098483 | 0.74 | MEN1 (0.40) | HTR2APTPN1PRKCBNR4A2SIRT2 | |
| SCHEMBL6094987 | 0.74 | MEN1 (0.41) | HTR2APRKCBNR4A2ATP4AATP4B | |
| SCHEMBL6094232 | 0.72 | AR (0.34) | HTR2APRKCBPRKCAPRKCHPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7057052-B2 | Heterocyclic quinones as pharmaceutical agents | DUKE UNIVERSITY (US) | 2006-06-06 | — | — | US | disclosed |
| WO-2004050014-A2 | SETEROCYCLIC QUINONES AS PHARMACEUTICAL AGENTS | DUKE UNIVERSITY (US) | 2004-06-17 | — | — | WO | disclosed |
| US-20040063774-A1 | Heterocyclic quinones as pharmaceutical agents | DUKE UNIVERSITY | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063774-A1 | Heterocyclic quinones as pharmaceutical agents | NQO1, RECQL, SDHA | HTR2A 1843/4885GPR84 4654/4885PTPRC 2035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.