Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 5/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 3/20 | 0.54 |
| ▸ | PRKCA | P17252 | 2/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.54 |
| ▸ | CDK4 | P11802 | 2/20 | 0.54 |
| ▸ | PRKACA | P17612 | 2/20 | 0.54 |
| ▸ | PRKACG | P22612 | 2/20 | 0.54 |
| ▸ | PRKACB | P22694 | 2/20 | 0.54 |
| ▸ | CCND1 | P24385 | 2/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.54 |
| ▸ | CDK2 | P24941 | 2/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | PRKCH | P24723 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098311 | 0.83 | F7 (0.43) | CAMK2DMEN1KMT2A | |
| SCHEMBL6094956 | 0.83 | ALDH1A1 (0.43) | PRKCBSIRT2PIM1PRKCACCNE2 | |
| SCHEMBL6094623 | 0.81 | IMPDH2 (0.45) | CCNE2CDK4PRKACAPRKACGPRKACB | |
| SCHEMBL6095486 | 0.81 | TDO2 (0.46) | CCNE2CDK4PRKACAPRKACGPRKACB | |
| SCHEMBL6098129 | 0.81 | EGFR (0.44) | PIM1PRKACAPRKACGPRKACBCAMK2D | |
| SCHEMBL6098483 | 0.81 | MEN1 (0.40) | PRKCBSIRT2PIM1PRKCACCNE2 | |
| SCHEMBL6095976 | 0.81 | TSHR (0.39) | PTPN1MEN1KMT2APDGFRB | |
| SCHEMBL6095205 | 0.81 | CSNK2A2 (0.41) | PRKCBSIRT2PIM1PRKCACCNE2 | |
| SCHEMBL6096429 | 0.81 | IGF1R (0.44) | PIM1CAMK2DPDGFRB | |
| SCHEMBL6094987 | 0.81 | MEN1 (0.41) | PRKCBMEN1HTTKMT2APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7057052-B2 | Heterocyclic quinones as pharmaceutical agents | DUKE UNIVERSITY (US) | 2006-06-06 | — | — | US | disclosed |
| WO-2004050014-A2 | SETEROCYCLIC QUINONES AS PHARMACEUTICAL AGENTS | DUKE UNIVERSITY (US) | 2004-06-17 | — | — | WO | disclosed |
| US-20040063774-A1 | Heterocyclic quinones as pharmaceutical agents | DUKE UNIVERSITY | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063774-A1 | Heterocyclic quinones as pharmaceutical agents | NQO1, RECQL, SDHA | PRKCB 4438/4885SIRT2 317/4885PIM1 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.