SCHEMBL60946

SCHEMBL60946

CC1=Cc2ccccc2[CH]1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.40
TSHR P16473 2/20 0.40
LMNA P02545 1/20 0.40
ALOX12 P18054 1/20 0.40
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22499662 0.97 ACHE (0.38) ACHETSHRLMNAALOX12TDP1
SCHEMBL28723720 0.90 LMNA (0.33) ACHETSHRLMNAALOX12
SCHEMBL5076757 0.70 TDP1 (0.39) ACHETDP1CYP1A2
SCHEMBL1651619 0.69
SCHEMBL7943843 0.69 LMNA (0.30) ACHETSHRLMNAALOX12
SCHEMBL21207302 0.69 LMNA (0.33) ACHETSHRLMNAALOX12
SCHEMBL11568990 0.69 LMNA (0.40) ACHETSHRLMNAALOX12TDP1
SCHEMBL5079303 0.69 CYP2A6 (0.36) ACHETSHRCYP1A2
SCHEMBL756303 0.67 CA1 (0.39) ACHETSHRLMNAALOX12TDP1
SCHEMBL5084873 0.67 LMNA (0.30) ACHETSHRLMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2732 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4388019-A1 MODULATING CO-MONOMER SELECTIVITY USING NON-COVALENT DISPERSION INTERACTIONS IN GROUP 4 OLEFIN POLYMERIZATION CATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-06-26 EP claimed
CN-118084987-A Silicon bridged neutral ligand-containing side arm single metallocene complex and application thereof 贝欧亿(山东)新材料有限公司 2024-05-28 CN claimed
CN-114891137-B Binuclear group IV metal catalyst for olefin polymerization, and preparation method, composition and application thereof 中国科学院长春应用化学研究所 2024-04-09 CN claimed
CN-117769573-A Regulation of comonomer selectivity in group 4 olefin polymerization catalysts using non-covalent dispersive interactions 切弗朗菲利浦化学公司 2024-03-26 CN claimed
US-11859041-B2 Modulating co-monomer selectivity using non-covalent dispersion interactions in group 4 olefin polymerization catalysts CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-01-02 US claimed
CN-114933665-B Heterometal binuclear catalyst and preparation method, composition and application thereof 中国科学院长春应用化学研究所 2023-11-21 CN claimed
CN-116589614-A Method for preparing COF-supported olefin polymerization catalyst 浙江大学衢州研究院 2023-08-15 CN claimed
CN-116209683-A Method for delivering non-aromatic solutions to a polymerization reactor 埃克森美孚化学专利公司 2023-06-02 CN claimed
US-20230098789-A1 MODULATING CO-MONOMER SELECTIVITY USING NON-COVALENT DISPERSION INTERACTIONS IN GROUP 4 OLEFIN POLYMERIZATION CATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-03-30 US claimed
WO-2023023455-A1 MODULATING CO-MONOMER SELECTIVITY USING NON-COVALENT DISPERSION INTERACTIONS IN GROUP 4 OLEFIN POLYMERIZATION CATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-02-23 WO claimed
US-5726333-A POLYMERIZATION CATALYSTS HOECHST AG (DE) 1998-03-10 US claimed
WO-1997043294-A1 YTTRIUM CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1997-11-20 WO claimed
WO-1997043268-A1 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS GEORGETOWN UNIVERSITY (US) 1997-11-20 WO claimed
US-5677255-A COMPLEX OF GROUP 4A METAL ON ORGANOSILICON POLYMER DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-14 US claimed
CN-1151172-A Polypropylene-higher alpha olefin copolymer articles EXXON CHEMICAL PATENTS INC (US) 1997-06-04 CN claimed
EP-0728773-A1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-28 EP claimed
US-5521265-A SUBSTITUTED WITH FERROCENE OR RUTHENOCENE, OLEFIN POLYMERIZATION PCD POLYMERE GESELLSCHAFT M.B.H. (AT) 1996-05-28 US claimed
EP-0673946-A2 Metallocenes and their use in polymerization of olefins PCD-Polymere Gesellschaft m.b.H. (AT) 1995-09-27 EP claimed
CN-1083490-A Olefin polymerization catalysis SPHERILENE SRL (IT) 1994-03-09 CN claimed
EP-0575875-A2 Catalysts for the polymerization of olefins Montell Technology Company bv (NL) 1993-12-29 EP claimed