SCHEMBL756303

SCHEMBL756303

COC1=Cc2ccccc2[CH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.39
CA2 P00918 4/20 0.39
CA7 P43166 3/20 0.39
CA9 Q16790 3/20 0.39
CA4 P22748 2/20 0.39
CA12 O43570 2/20 0.39
CA14 Q9ULX7 2/20 0.39
ALDH1A1 P00352 5/20 0.36
KDM4E B2RXH2 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 2/20 0.36
PTGS2 P35354 2/20 0.33
CYP1A2 P05177 3/20 0.32
TP53 P04637 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
CYP2C19 P33261 2/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 2/20 0.32
CDC25A P30304 2/20 0.32
CDC25B P30305 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5692487 0.74 GPR84 (0.32)
SCHEMBL217368 0.73
SCHEMBL10435816 0.70 HTR2C (0.35) CA1CA2CA7CA9CA12
SCHEMBL5916035 0.70 PTPN1 (0.46) CA1CA2CA7CA9CA4
SCHEMBL5077511 0.69
SCHEMBL3858056 0.69 CA1 (0.38) CA1CA2CA7CA9CA4
SCHEMBL7940884 0.68 CA12 (0.32) CA1CA9CA12
SCHEMBL60946 0.67 ACHE (0.40) CYP1A2TDP1TSHRLMNAACHE
SCHEMBL1651619 0.65
SCHEMBL7943843 0.65 LMNA (0.30) TSHRLMNAACHEALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019196720-A1 ARGININE METHYLTRANSFERASE INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 中国科学院上海药物研究所 2019-10-17 WO claimed
EP-0795564-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2001-01-10 EP claimed
US-5925717-A SELECTIVE HYDROGENATION OF POLYMERS WITH TITANIUM CATALYSTS WITH INDENE COMPOUND LIGANDS SHELL OIL COMPANY (US) 1999-07-20 US claimed
EP-0795564-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP claimed
CN-110799868-B Liquid crystal film, optical laminate, circularly polarizing plate, and organic electroluminescent display device 富士胶片株式会社 2022-02-22 CN disclosed
US-11230669-B2 Liquid crystal film, optical laminate, circularly polarizing plate, and organic electroluminescent display device FUJIFILM CORPORATION (JP) 2022-01-25 US disclosed
US-20200109333-A1 LIQUID CRYSTAL FILM, OPTICAL LAMINATE, CIRCULARLY POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-04-09 US disclosed
CN-110799868-A Liquid crystal film, optical laminate, circularly polarizing plate, and organic electroluminescent display device 富士胶片株式会社 2020-02-14 CN disclosed
WO-2019196720-A1 ARGININE METHYLTRANSFERASE INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 中国科学院上海药物研究所 2019-10-17 WO disclosed
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
EP-2235072-B1 USE OF POLYOLEFINS HAVING ISOTACTIC STRUCTURAL ELEMENTS IN FLOORING MATERIALS EVONIK DEGUSSA GMBH (DE) 2016-04-20 EP disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed
EP-0795564-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2001-01-10 EP disclosed
US-5925717-A SELECTIVE HYDROGENATION OF POLYMERS WITH TITANIUM CATALYSTS WITH INDENE COMPOUND LIGANDS SHELL OIL COMPANY (US) 1999-07-20 US disclosed
US-5817670-A RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1998-10-06 US disclosed
EP-0795564-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP disclosed
EP-0779292-A1 NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1997-06-18 EP disclosed