Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.49 |
| ▸ | PPARG | P37231 | 10/20 | 0.49 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092849 | 1.00 | PPARA (0.49) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3115799 | 0.82 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL6092990 | 0.79 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL6092781 | 0.79 | PPARA (0.47) | PPARAPPARGPPARD | |
| Tert-Butylamine SCHEMBL3112027 | 0.77 | PPARA (0.68) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3100619 | 0.77 | PPARA (0.71) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3100628 | 0.77 | PPARA (0.71) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3946198 | 0.77 | PPARA (0.71) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5474463 | 0.76 | PPARA (0.70) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL14584453 | 0.76 | PPARG (0.69) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199857-A1 | Therapeutic agents | ASTRAZENECA UK LIMITED (GB) | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199857-A1 | Therapeutic agents | PNLIP, LIPC, GPR119 | PPARA 27/4885PPARG 38/4885PPARD 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.