Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22739278 | 0.81 | SMN1; SMN2 (0.38) | MAOATTRCES1ALDH1A1 | |
| SCHEMBL29390564 | 0.81 | MAOA (0.60) | MAOATTRCES1LMNAALDH1A1 | |
| SCHEMBL482716 | 0.81 | MAOA (0.60) | MAOATTRCES1LMNAALDH1A1 | |
| SCHEMBL4571020 | 0.81 | MAOA (0.60) | MAOATTRCES1LMNAALDH1A1 | |
| SCHEMBL13636983 | 0.81 | — | — | |
| SCHEMBL16786519 | 0.75 | MAOA (0.48) | MAOATTRCES1LMNAALDH1A1 | |
| SCHEMBL14421169 | 0.72 | CA12 (0.44) | LMNAALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL13866805 | 0.71 | MAPT (0.38) | LMNAALDH1A1L3MBTL1GAAMCL1 | |
| SCHEMBL16519629 | 0.71 | ADORA3 (0.37) | ALDH1A1 | |
| SCHEMBL12660037 | 0.71 | NR1H2 (0.44) | LMNAALDH1A1L3MBTL1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872225-B2 | Pyruvate kinase modulators and use thereof | AGIOS PHARMACEUTICALS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| EP-4265666-A1 | DIBORANE-BASED, METAL-FREE CATALYST SYSTEMS FOR THE PREPARATION OF ISOTACTIC-ENRICHED ALIPHATIC POLYETHERS, RELATED PROCESS, POLYETHER OBTAINED BY THE PROCESS AND USE OF THE CATALYST SYSTEMS | Universität Stuttgart (DE) | 2023-10-25 | — | — | EP | disclosed |
| WO-2023135603-A1 | MODULATORS OF SK4 POTASSIUM CHANNEL AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-07-20 | — | — | WO | disclosed |
| US-7132550-B2 | Process for the preparation of cyanine dyes with polysulfonate anions | EASTMAN KODAK COMPANY (US) | 2006-11-07 | — | — | US | disclosed |
| EP-1535968-A2 | Process for the preparation of cyanine dyes with polysulfonate anions | Kodak Polychrome Graphics, LLC (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20050113546-A1 | Process for the preparation of cyanine dyes with polysulfonate anions | KODAK REALTY INC. | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11872225-B2 | Pyruvate kinase modulators and use thereof | PDK1, PDK2, PDK4 | MAOA 3679/4885TTR 3087/4885CES1 553/4885 |
| US-20050113546-A1 | Process for the preparation of cyanine dyes with polysulfonate anions | MPST, ALG3, KIT | MAOA 3895/4885TTR 2969/4885CES1 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.