Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099049 | 0.89 | CTSA (0.50) | CYP26A1CTSAFFAR1EEF2K | |
| SCHEMBL6097767 | 0.88 | CTSA (0.51) | MMECTSAFFAR1EEF2K | |
| SCHEMBL5926264 | 0.86 | L3MBTL1 (0.43) | CYP26A1MMEP2RX1TMPRSS4CTSA | |
| SCHEMBL6097852 | 0.86 | CTSA (0.52) | MMECTSAFFAR1 | |
| SCHEMBL6098436 | 0.85 | CTSA (0.51) | CYP26A1MMECTSAFFAR1 | |
| SCHEMBL6095738 | 0.85 | KIFC1 (0.52) | MMEP2RX1TMPRSS4MEN1LMNA | |
| SCHEMBL6100717 | 0.84 | MME (0.49) | MMECTSAFFAR1 | |
| SCHEMBL5926837 | 0.83 | P2RX1 (0.45) | P2RX1TMPRSS4MEN1LMNAMAPT | |
| SCHEMBL4831680 | 0.83 | TACR3 (0.48) | CYP26A1MMECTSAMEN1LMNA | |
| SCHEMBL5926866 | 0.82 | ABCB1 (0.48) | CYP26A1MMEP2RX1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |