Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 13/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 13/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 13/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 13/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 13/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 13/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299712 | 0.81 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13424739 | 0.81 | GRIN2D (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7012269 | 0.80 | GRIN2D (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15957619 | 0.72 | GPR35 (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8896851 | 0.71 | GRIN2D (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9846189 | 0.70 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9446333 | 0.70 | GPR35 (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13212272 | 0.70 | IMPDH2 (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL18425074 | 0.69 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1674394 | 0.69 | MEN1 (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100402528-C | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-07-16 | — | — | CN | disclosed |
| CN-101220028-A | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-07-16 | — | — | CN | disclosed |
| CN-100387597-C | Amido-substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-100372846-C | Sulfonamido substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-03-05 | — | — | CN | disclosed |
| US-7098221-B2 | Amide substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-08-29 | — | — | US | disclosed |
| CN-1249062-C | Substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2006-04-05 | — | — | CN | disclosed |
| US-20050282854-A1 | Amide substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2005-12-22 | — | — | US | disclosed |
| US-6969722-B2 | Amide substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-11-29 | — | — | US | disclosed |
| US-6903113-B2 | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-07 | — | — | US | disclosed |
| US-6878719-B2 | Sulfonamido substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-12 | — | — | US | disclosed |
| US-6545016-B1 | Inducing cytokine biosynthesis; treating a viral and neoplastic diseases | 3M INNOVATIVE PROPERTIES COMPANY | 2003-04-08 | — | — | US | disclosed |
| US-6525064-B1 | Immune response modifiers; can induce the biosynthesis of various cytokines; | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-25 | — | — | US | disclosed |
| US-20020107262-A1 | SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY | 2002-08-08 | — | — | US | disclosed |
| WO-2002046194-A2 | SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |
| EP-0708772-B1 | IMIDAZO [4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING & MFG (US) | 2000-08-23 | — | — | EP | disclosed |
| US-5644063-A | VIRICIDES AND INDUCTION OF INTERFERON BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0708772-A1 | IMIDAZO [4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5494916-A | VIRICIDES, AGENTS THAT INDUCE INTERFERON BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-27 | — | — | US | disclosed |
| US-5446153-A | For inducing interferon biosynthesis; immunomodulators | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| WO-1995002597-A1 | IMIDAZO[4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282854-A1 | Amide substituted imidazopyridines | IRF3, EIF2AK2, IFNG | GRIN2D 4355/4885GRIN3B 3020/4885GRIN1 2664/4885 |
| US-20020107262-A1 | SUBSTITUTED IMIDAZOPYRIDINES | IRF3, IFNG, EIF2AK2 | GRIN2D 4381/4885GRIN3B 2414/4885GRIN1 2783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.