Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27272353 | 0.95 | LTA4H (0.50) | LTA4HNCOA1NCOA3ALDH1A1NPC1 | |
| SCHEMBL27652302 | 0.89 | LTA4H (0.47) | LTA4HALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL8129827 | 0.89 | NCOA1 (0.47) | LTA4HNCOA1NCOA3ALDH1A1MEN1 | |
| SCHEMBL6098407 | 0.84 | MAPT (0.42) | NCOA1NCOA3ALDH1A1NPC1RAB9A | |
| SCHEMBL693820 | 0.83 | CA12 (0.39) | ALDH1A1NPC1RAB9AMEN1MAPT | |
| SCHEMBL9775715 | 0.82 | AR (0.44) | LTA4HALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL9268604 | 0.82 | ABL1 (0.42) | MAPTKMT2ABACE1CYP1A2CYP2C9 | |
| SCHEMBL6777000 | 0.81 | CYP1A1 (0.41) | LTA4HALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6099374 | 0.81 | NCOA1 (0.51) | LTA4HNCOA1NCOA3ALDH1A1NPC1 | |
| SCHEMBL6098760 | 0.81 | KIF11 (0.43) | NCOA1NCOA3ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | claimed |