SCHEMBL9775715

SCHEMBL9775715

COc1ccc(Oc2c[c]ccc2-c2cccc(Oc3ccccc3C)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.44
CYP1A2 P05177 3/20 0.40
CYP2C9 P11712 3/20 0.40
CYP2C19 P33261 3/20 0.40
CYP1A1 P04798 1/20 0.40
CYP2E1 P05181 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C8 P10632 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP4B1 P13584 1/20 0.40
CYP2B6 P20813 1/20 0.40
CYP3A5 P20815 1/20 0.40
CYP2A7 P20853 1/20 0.40
CYP3A7 P24462 1/20 0.40
CYP2F1 P24903 1/20 0.40
CYP2C18 P33260 1/20 0.40
CYP2J2 P51589 1/20 0.40
CYP4F2 P78329 1/20 0.40
CYP4F8 P98187 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27652302 0.90 LTA4H (0.47) CYP1A2CYP2C9CYP2C19CYP1A1CYP2E1
SCHEMBL6777000 0.88 CYP1A1 (0.41) ARCYP1A2CYP2C9CYP2C19CYP1A1
SCHEMBL6096838 0.82 LTA4H (0.47) CYP1A2CYP2C9CYP2C19CYP1A1CYP2E1
SCHEMBL27272353 0.81 LTA4H (0.50) CYP1A2CYP2C9CYP2C19POLBGAA
SCHEMBL9775712 0.79 AR (0.44) ARCYP1A2CYP2C9CYP2C19POLB
SCHEMBL733149 0.78 CYP1A1 (0.56) CYP1A2CYP2C9CYP2C19CYP1A1CYP2E1
SCHEMBL7017887 0.78 CYP1A2 (0.39) CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6
SCHEMBL3536486 0.75 CYP1A1 (0.44) CYP1A2CYP2C9CYP2C19CYP1A1CYP2E1
SCHEMBL8129827 0.74 NCOA1 (0.47) ARCYP1A2CYP2C9CYP2C19GAA
SCHEMBL2321472 0.74 ALDH1A1 (0.61) ARCYP1A2CYP2C9CYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5002957-A Insecticides, acaricides, nematocides HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-26 US disclosed