Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | NMBR | P28336 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966865 | 0.84 | KMT2A (0.43) | ALDH1A1DRD4DRD3LMNAHPGDS | |
| SCHEMBL29966872 | 0.81 | TUBB4A (0.42) | ALDH1A1DRD4DRD3LMNA | |
| SCHEMBL27351323 | 0.80 | CASP1 (0.65) | CASP1ALDH1A1LMNA | |
| SCHEMBL10627511 | 0.79 | ATM (0.48) | CASP1NMBRTACR1LMNAMAPT | |
| SCHEMBL6099297 | 0.79 | PTGS2 (0.42) | MAPT | |
| SCHEMBL29966571 | 0.79 | PTGS2 (0.42) | MAPT | |
| SCHEMBL7425563 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPK14ENPP2MMP2MMP9 | |
| SCHEMBL28662043 | 0.75 | TDP1 (0.53) | CASP1ALDH1A1LMNA | |
| SCHEMBL6099865 | 0.75 | MAPT (0.44) | ALDH1A1DRD4DRD3NMBRTACR1 | |
| SCHEMBL6377537 | 0.75 | MAPT (0.38) | ALDH1A1ENPP2DRD4DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153852-B2 | Indole compounds, process for producing the same and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-12-26 | — | — | US | disclosed |