Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.43 |
| ▸ | RXRB | P28702 | 5/20 | 0.43 |
| ▸ | RXRG | P48443 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098407 | 0.80 | MAPT (0.42) | L3MBTL1RAB9ATP53POLBGSTP1 | |
| SCHEMBL4364262 | 0.75 | KIF11 (0.39) | RAB9ATP53 | |
| SCHEMBL6525290 | 0.75 | ADRB2 (0.41) | L3MBTL1RAB9ATP53MAPTMAPK1 | |
| SCHEMBL6154800 | 0.75 | APP (0.54) | RXRARXRBL3MBTL1RAB9AAPP | |
| SCHEMBL27696667 | 0.75 | RXRA (0.50) | RXRARXRBRXRGL3MBTL1MRGPRX4 | |
| SCHEMBL5782738 | 0.74 | KIF11 (0.37) | RAB9ATP53MAPT | |
| SCHEMBL27807745 | 0.73 | XDH (0.40) | RXRARXRBL3MBTL1RAB9AAPP | |
| SCHEMBL12301141 | 0.72 | RXRA (0.58) | RXRARXRBRXRGL3MBTL1RAB9A | |
| SCHEMBL6667569 | 0.72 | DRD1 (0.44) | RXRARXRBRXRGL3MBTL1RAB9A | |
| SCHEMBL10181128 | 0.71 | RXRA (0.56) | RXRARXRBRXRGL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | claimed |