7,8-Dihydropteroate

7,8-Dihydropteroate

SCHEMBL609952

Nc1nc(=O)c2c([nH]1)NCC(CNc1ccc(C(=O)O)cc1)=N2

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
CYP1A2 P05177 1/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 2/20 0.38
TYMS P04818 2/20 0.35
CCNE1 P24864 1/20 0.35
CDK2 P24941 1/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
AKR1B1 P15121 1/20 0.35
PTGS2 P35354 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
DHFR P00374 2/20 0.34
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
SOST Q9BQB4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7,8-Dihydropteroate SCHEMBL1332736 0.83 KDM4E (0.44) TSHRCYP1A2KDM4EPOLBTYMS
7,8-Dihydropteroate SCHEMBL26116637 0.80 KDM4E (0.41) TSHRCYP1A2KDM4EPOLBTYMS
SCHEMBL15298747 0.78 DHFR (0.37) TSHRKDM4EPOLBTYMSALDH1A1
7,8-Dihydropteroate SCHEMBL25432562 0.77 KDM4E (0.41) TSHRCYP1A2KDM4EPOLBTYMS
7,8-Dihydropteroate SCHEMBL29752623 0.77 KDM4E (0.39) TSHRCYP1A2KDM4EPOLBTYMS
7,8-Dihydropteroate SCHEMBL13772569 0.76 CYP1A2 (0.37) TSHRCYP1A2KDM4EPOLBCCNE1
SCHEMBL851106 0.74 KDM4E (0.32) KDM4EMEN1KMT2AHSD17B10DHFR
SCHEMBL17548881 0.73 TYMS (0.47) TSHRKDM4EPOLBTYMSALDH1A1
SCHEMBL13189927 0.73 CYP1A2 (0.37) TSHRCYP1A2KDM4EPOLBCCNE1
Dihydrofolic Acid SCHEMBL8281 0.70 SOST (0.61) TSHRKDM4EPOLBTYMSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025124444-A1 USE OF HYDROXYPROLINE AND DERIVATIVE THEREOF, BIOLOGICAL HERBICIDE, BROAD-SPECTRUM HERBICIDE, AND WEED CONTROL METHOD 三亚市国家耐盐碱水稻技术创新中心 2025-06-19 WO claimed
US-20240130368-A1 HERBICIDAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2024-04-25 US claimed
EP-4316244-A1 HERBICIDAL COMPOSITION Nippon Soda Co., Ltd. (JP) 2024-02-07 EP claimed
WO-2023233398-A1 HERBICIDAL MIXTURE, HERBICIDAL COMPOSITION, METHOD, USE, AND KITS FOR CONTROLLING UNDESIRABLE VEGETATION ADAMA AGAN LTD. (IL) 2023-12-07 WO claimed
US-11812738-B2 Polynucleotide molecules for gene regulation in plants MONSANTO TECHNOLOGY LLC (US) 2023-11-14 US claimed
CN-116354953-A Herbicidal composition containing benzothiazole compounds 西北农林科技大学 2023-06-30 CN claimed
US-11083192-B2 Fertilizer and agrochemical formulation MITSUI CHEMICALS AGRO, INC. (JP) 2021-08-10 US claimed
US-10568328-B2 Methods and compositions for weed control MONSANTO TECHNOLOGY LLC (US) 2020-02-25 US claimed
US-20190320651-A1 FERTILIZER AND AGROCHEMICAL FORMULATION MITSUI CHEMICALS AGRO, INC. (JP) 2019-10-24 US claimed
US-10375951-B2 Fertilizer and agrochemical formulation MITSUI CHEMICALS AGRO, INC. (JP) 2019-08-13 US claimed
CN-101325875-A Method of controlling weeds BASF AG (DE) 2008-12-17 CN claimed
CN-101282642-A Herbicidal compositions based on 3-phenyluracils and n-[[4-[(cyclopropylamino)-carbonyl]phenyl]sulfonyl]-2-methoxybenzamide BASF SE (DE) 2008-10-08 CN claimed
CN-101232813-A A method of controlling weeds BASF SE (DE) 2008-07-30 CN claimed
CN-101232811-A Method for controlling weeds BASF SE (DE) 2008-07-30 CN claimed
WO-2008089102-A2 COMPOSITIONS AND METHODS FOR ENHANCING TOLERANCE FOR THE PRODUCTION OF ORGANIC CHEMICALS PRODUCED BY MICROORGANISMS REGENTS OF THE UNIVERSITY OF COLORADO (US) 2008-07-24 WO claimed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 WO claimed
US-20030023386-A1 Metabolome profiling methods using chromatographic and spectroscopic data in pattern recognition analysis BASF AKTIENGESELLSCHAFT (DE) 2003-01-30 US claimed
CN-1376198-A Polynucleotide sequences and their use in a method of producing plants with an increased number of stomata ZENECA LTD (GB) 2002-10-23 CN claimed
WO-2002057989-A2 METHOD FOR METABOLIC PROFILING BASF AKTIENGESELLSCHAFT (DE) 2002-07-25 WO claimed
US-5633444-A A GENETICALLY ENGINEERED PLANT CELL RHONE-POULENC AGROCHIMIE LIMITED (FR) 1997-05-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240130368-A1 HERBICIDAL COMPOSITION CHRM2, DDT, CHRM1 TSHR 74/4885CYP1A2 468/4885KDM4E 863/4885
US-10568328-B2 Methods and compositions for weed control CYC1, PRDX5, CYCS TSHR 4266/4885CYP1A2 1213/4885KDM4E 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.