7,8-Dihydropteroate

7,8-Dihydropteroate

SCHEMBL1332736

Nc1nc2c(c(=O)[nH]1)N=C(CNc1ccc(C(=O)O)cc1)CN2

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD17B10 Q99714 2/20 0.44
RGS12 O14924 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
CASP1 P29466 1/20 0.44
BLM P54132 1/20 0.44
CASP7 P55210 1/20 0.44
GNAI1 P63096 1/20 0.44
HIF1A Q16665 1/20 0.44
TYMS P04818 2/20 0.39
SOST Q9BQB4 1/20 0.39
TSHR P16473 2/20 0.38
CYP1A2 P05177 1/20 0.38
FPGS Q05932 2/20 0.38
POLB P06746 2/20 0.38
CCNE1 P24864 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7,8-Dihydropteroate SCHEMBL26116637 0.96 KDM4E (0.41) KDM4EMEN1KMT2AHSD17B10RGS12
7,8-Dihydropteroate SCHEMBL25432562 0.92 KDM4E (0.41) KDM4EMEN1KMT2AHSD17B10RGS12
7,8-Dihydropteroate SCHEMBL29752623 0.92 KDM4E (0.39) KDM4EMEN1KMT2AHSD17B10RGS12
SCHEMBL13189927 0.85 CYP1A2 (0.37) KDM4EMEN1KMT2ATSHRCYP1A2
SCHEMBL22430266 0.84 LMNA (0.40) KDM4EMEN1KMT2AHSD17B10RGS12
7,8-Dihydropteroate SCHEMBL609952 0.83 TSHR (0.38) KDM4EMEN1KMT2AHSD17B10TYMS
Dihydrofolic Acid SCHEMBL8282 0.83 SOST (0.61) KDM4EMEN1KMT2AHSD17B10TYMS
Dihydrofolic Acid SCHEMBL27589172 0.83 SOST (0.61) KDM4EMEN1KMT2AHSD17B10TYMS
Dihydrofolic Acid SCHEMBL8281 0.83 SOST (0.61) KDM4EMEN1KMT2AHSD17B10TYMS
7,8-Dihydropteroate SCHEMBL13772569 0.83 CYP1A2 (0.37) KDM4EKMT2AMAPTTSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119894374-A Use of alkyl ether sulphates for improving the efficacy of herbicides 巴斯夫欧洲公司 2025-04-25 CN claimed
CN-119677410-A Herbicidal compositions comprising azine compounds 巴斯夫欧洲公司 2025-03-21 CN claimed
EP-4522128-A1 METHOD FOR TREATING INFECTIOUS DISEASE Suntec Medical, Inc. (US) 2025-03-19 EP claimed
US-20240206459-A1 SYNERGISTIC AGROCHEMICAL OIL DISPERSION FORMULATION RAJDHANI PETROCHEMICALS PRIVATE LIMITED (IN) 2024-06-27 US claimed
WO-2023233398-A1 HERBICIDAL MIXTURE, HERBICIDAL COMPOSITION, METHOD, USE, AND KITS FOR CONTROLLING UNDESIRABLE VEGETATION ADAMA AGAN LTD. (IL) 2023-12-07 WO claimed
WO-2023220086-A1 METHOD FOR TREATING INFECTIOUS DISEASE SUNTEC MEDICAL, INC. (US) 2023-11-16 WO claimed
CN-110072853-B Herbicidal phenyltriazolinones 巴斯夫欧洲公司 2023-07-25 CN claimed
CN-116354953-A Herbicidal composition containing benzothiazole compounds 西北农林科技大学 2023-06-30 CN claimed
WO-2022224275-A1 SYNERGISTIC AGROCHEMICAL OIL DISPERSION FORMULATION RAJDHANI PETROCHEMICALS PRIVATE LIMITED (IN) 2022-10-27 WO claimed
CN-105916379-B The composition of the thio -3- of 1,5- dimethyl -6- (tri- fluoro- 3- oxos -4- (Propargyl) -3,4- dihydro -2H- benzos [b] [1,4] oxazine -6- bases of 2,2,7-) -1,3,5- triazine alkane -2,4- diketone 巴斯夫欧洲公司 2018-09-11 CN claimed
US-20150299742-A1 COMPOSITIONS AND METHODS FOR ENHANCING TOLERANCE FOR THE PRODUCTION OF ORGANIC CHEMICALS PRODUCED BY MICROORGANISMS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2015-10-22 US claimed
CN-101282642-B Herbicidal compositions based on 3-phenyluracils and n-[[4-[(cyclopropylamino)-carbonyl]phenyl]sulfonyl]-2-methoxybenzamide BASF SE 2012-12-12 CN claimed
US-20100210017-A1 COMPOSITIONS AND METHODS FOR ENHANCING TOLERANCE FOR THE PRODUCTION OF ORGANIC CHEMICALS PRODUCED BY MICROORGANISMS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2010-08-19 US claimed
EP-2126042-A2 COMPOSITIONS AND METHODS FOR ENHANCING TOLERANCE FOR THE PRODUCTION OF ORGANIC CHEMICALS PRODUCED BY MICROORGANISMS The Regents of the University of Colorado (US) 2009-12-02 EP claimed
CN-101346065-A Method for controlling aquatic weeds BASF SE (DE) 2009-01-14 CN claimed
CN-101325875-A Method of controlling weeds BASF AG (DE) 2008-12-17 CN claimed
CN-101282642-A Herbicidal compositions based on 3-phenyluracils and n-[[4-[(cyclopropylamino)-carbonyl]phenyl]sulfonyl]-2-methoxybenzamide BASF SE (DE) 2008-10-08 CN claimed
CN-101232813-A A method of controlling weeds BASF SE (DE) 2008-07-30 CN claimed
CN-101232811-A Method for controlling weeds BASF SE (DE) 2008-07-30 CN claimed
WO-2008089102-A2 COMPOSITIONS AND METHODS FOR ENHANCING TOLERANCE FOR THE PRODUCTION OF ORGANIC CHEMICALS PRODUCED BY MICROORGANISMS REGENTS OF THE UNIVERSITY OF COLORADO (US) 2008-07-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240206459-A1 SYNERGISTIC AGROCHEMICAL OIL DISPERSION FORMULATION DDT, SQLE, SCD KDM4E 2483/4885MEN1 3937/4885KMT2A 3500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.